Predicting Visual Sensitivity in Retinal Prosthesis Patients

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Predicting visual sensitivity in retinal prosthesis patients.

PURPOSE With the long-term goal of restoring functional vision in patients with retinal degenerative diseases, the eyes of blind human subjects were implanted chronically with epiretinal prostheses consisting of two-dimensional electrode arrays that directly stimulated cells of the neural retina. METHODS Psychophysical techniques were used to measure the brightness of electrically generated p...

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Reading Visual Braille with a Retinal Prosthesis

Retinal prostheses, which restore partial vision to patients blinded by outer retinal degeneration, are currently in clinical trial. The Argus II retinal prosthesis system was recently awarded CE approval for commercial use in Europe. While retinal prosthesis users have achieved remarkable visual improvement to the point of reading letters and short sentences, the reading process is still fairl...

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Visual and Non-Visual Navigation in Blind Patients with a Retinal Prosthesis

Human adults with normal vision can combine visual landmark and non-visual self-motion cues to improve their navigational precision. Here we asked whether blind individuals treated with a retinal prosthesis could also benefit from using the resultant new visual signal together with non-visual information when navigating. Four patients (blind for 15-52 years) implanted with the Argus II retinal ...

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High-Fidelity Reproduction of Spatiotemporal Visual Signals for Retinal Prosthesis

Natural vision relies on spatiotemporal patterns of electrical activity in the retina. We investigated the feasibility of veridically reproducing such patterns with epiretinal prostheses. Multielectrode recordings and visual and electrical stimulation were performed on populations of identified ganglion cells in isolated peripheral primate retina. Electrical stimulation patterns were designed t...

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Simulation of visual perception and learning with a retinal prosthesis

1Neurosurgery, Ophthalmology & Hansen Experimental Physics Laboratory, Stanford University, Stanford, CA 94305 USA 2School of Medicine, Stanford University, Stanford, CA 94305 USA 3Psychology, University of Pennsylvania, Philadelphia, PA 19104 USA 4Physiology & Biophysics, University of Washington, Seattle, WA 98105 USA 5Center for Image Systems Engineering, Stanford University, Stanford, CA 94...

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ژورنال

عنوان ژورنال: Investigative Opthalmology & Visual Science

سال: 2009

ISSN: 1552-5783

DOI: 10.1167/iovs.08-2595